Constipation In other cases, digestion becomes sluggish overall, making bowel movements less frequent and harder to pass
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iPSCs derived from patients with SNCA mutations exhibit intracellular aggregation of -syn, leading to impaired anterograde axonal transport of mitochondria due to loss of nuclear factor erythroid-2 related factor 2 (Nrf2) transcriptional activity
doi:10.1152/ajplung.00273.2021
